Dengue disproportionately affects tropical and subtropical regions, particularly urban and semi-urban areas. Severe cases can lead to hospitalization and, in rare instances, death. Vulnerable populations, including children and those with prior dengue infections, are at higher risk of severe outcomes. The economic and healthcare burden is significant, with fragile health systems struggling to manage outbreaks. Climate change and urbanization have expanded the range of Aedes mosquitoes, increasing the risk of transmission in previously unaffected areas.