The Nipah virus poses significant health risks, with case fatality rates often exceeding 60%. Kerala's recurrent spillovers are linked to bat roosts near human settlements, increasing exposure to contaminated fruit. West Bengal faces risks from raw date palm sap consumption during the harvesting season, which has led to nosocomial transmission in healthcare settings. Healthcare workers remain particularly vulnerable, as demonstrated by recent cases in Barasat, West Bengal. The ecological and seasonal factors driving these outbreaks underscore the need for region-specific interventions to mitigate spillover risks. Without sustained surveillance and infection control measures, the potential for larger outbreaks remains a concern.