The study underscores the severe impact of heat and drought on wheat yields, particularly during sensitive growth stages. With rising global temperatures and increasing water scarcity, wheat production in regions like India could face significant challenges. The identification of stress-tolerant genetic markers offers a pathway to mitigate these risks. However, the research also highlights the complexity of breeding for multiple stress tolerances, given the intricate genetic and environmental interactions. Farmers in heat-prone and drought-affected areas may experience reduced yields if adaptive measures are not implemented.