The presence of 6PPD-quinone in Indian urban environments could pose significant risks to aquatic ecosystems, particularly during intense rainfall events. With India becoming the world's third-largest automobile market, tyre wear particles are likely increasing, potentially contaminating water bodies already under stress from urban discharge. Experts highlight the urgency of addressing this issue, as the compound ranks among the most toxic chemicals for aquatic life globally. Without proper monitoring and regulation, the environmental and public health impacts could worsen.