The extreme heat will affect millions across the central U.S., particularly in cities like Kansas City, St. Louis, and Memphis. The combination of high temperatures and humidity will result in dangerous RealFeel® Temperatures exceeding 110°F (43.3°C) in some areas, increasing the risk of heat-related illnesses such as heat cramps, heat exhaustion, and heat stroke. Vulnerable populations, including the elderly, children, and those with pre-existing health conditions, are at heightened risk. Outdoor workers and individuals without access to air conditioning should take extra precautions.