The tornado caused catastrophic damage to infrastructure, homes, and businesses in the Fox Cities area. Menasha experienced the most severe destruction, including the complete loss of Manderfield's Home Bakery. Power outages affected nearly 46,000 customers across Wisconsin, with significant disruptions in Calumet, Outagamie, and Winnebago counties. Downed power lines and blocked roadways have complicated recovery efforts. While no fatalities have been reported, the scale of destruction has left many neighborhoods unrecognizable, posing challenges for residents and emergency responders.