The heat dome poses significant risks to public health and infrastructure, particularly in the northern Plains, Upper Midwest, and parts of the East. Prolonged exposure to high temperatures and humidity can lead to heat-related illnesses such as heat exhaustion and heat stroke. Vulnerable populations, including the elderly, children, and those with pre-existing health conditions, are at heightened risk. Overnight temperatures in the mid to upper 70s°F (24°C to 27°C) will provide little relief, further stressing cooling systems and increasing energy demand. The National Weather Service emphasizes the importance of monitoring heat indices, which could reach hazardous levels of 105°F to 110°F (40°C to 43°C).