The Gulf Coast faces multiple risks from Hurricane Isaias, including tropical-storm-force winds, heavy rainfall, and localized flooding. Coastal areas may experience dangerous surf conditions and life-threatening rip currents. Power outages and downed trees are possible, especially near Mobile Bay and the western Florida Panhandle. Tornadoes could develop in the storm's outer bands, particularly on Saturday. Residents in flood-prone areas should prepare for rapid water rises and urban flooding.