The projected water scarcity will disproportionately affect densely populated and agriculturally dependent regions, such as South Asia and Sub-Saharan Africa. Poor water quality and insufficient supply could exacerbate public health issues, economic instability, and food insecurity. The manufacturing and irrigation sectors are particularly at risk, with significant implications for global food production and industrial operations. Vulnerable populations, including those in arid regions like central Australia and northern Canada, may face heightened sensitivity to water availability changes, further stressing local ecosystems and livelihoods.