The high salinity levels in these rivers pose challenges for water management and supply in affected regions. For example, the South Fork Wichita River's salinity prompted a federal project to intercept and evaporate brine to protect downstream water sources. Similarly, the Prairie Dog Town Fork Red River and Pease River systems have seen efforts to mitigate chloride loads. These conditions can impact agriculture, drinking water supplies, and aquatic ecosystems, particularly in areas with limited freshwater availability for dilution.