The rising incidence of dengue poses significant health risks, particularly in tropical and subtropical regions. Vulnerable populations, including those in urban and semi-urban areas, face increased exposure due to environmental and social factors. Severe dengue, which can lead to hospitalization and death, is more likely in individuals with prior infections. The disease's spread to new areas, including parts of Europe, highlights the growing global threat. Health systems in affected regions are under strain, and the economic burden of managing outbreaks is substantial. Climate change and urbanization are expected to exacerbate these challenges.