A major vehicle pileup involving over 75 vehicles, including semi-trucks, has resulted in the closure of eastbound Interstate 70 in Colorado due to snowy conditions. The incident has caused significant disruption to traffic flow, with highway officials closing the affected section of the interstate and leading to substantial delays for commuters and transport services. Motorists are advised to avoid the area and seek alternative routes, with the Colorado Department of Transportation (CDOT) providing updates on the closure and estimated reopening times.