Dengue poses a significant health risk to travelers and residents in affected regions, particularly in tropical and subtropical climates. The disease can range from mild to severe, with severe cases potentially leading to hospitalization or death. Travelers returning to the U.S. from high-risk areas have also been identified with dengue, underscoring the global nature of the threat. The risk is heightened in areas with poor mosquito control and during peak mosquito activity. Individuals who have previously been infected with dengue are at greater risk of developing severe symptoms upon reinfection.