Individuals taking SSRIs, diuretics, or ADHD medications are at a higher risk of heat-related illnesses, particularly during strenuous outdoor activities or prolonged heat exposure. The elderly and those with pre-existing health conditions are especially vulnerable. Heat stroke and heat exhaustion are potential risks, and improper storage of medications in hot or humid conditions can lead to reduced efficacy. These factors underscore the need for heightened awareness and precaution during extreme heat events.