The success of 'Avengers: Doomsday' could reinvigorate the Marvel Cinematic Universe (MCU), which has faced challenges in recent years. High pre-sales and trailer views indicate strong audience interest, but competition with 'Dune: Part III' for premium screens like IMAX may impact its box office performance. Marvel's introduction of 'Infinity Vision' as an alternative to IMAX could face skepticism from discerning moviegoers, potentially affecting the film's reception.